The Startup Game has a post exploring how Web 2.0 "online powerpoint" startup Zenter was successful in being acquired by Google.

Here's one of the interesting tips:

Don't be afraid to tackle the giants. Big companies like eBay (EBAY) and Microsoft (MSFT) may have more manpower and financial resources, but they also have disadvantages. "Often times, they're not as driven. They're not willing to make the sacrifice, like two guys sleeping on air mattresses, to make their product really good," says Graham. Case in point. Google bought YouTube, which was far superior to Google Video. eBay bought PayPal because clearly, no one was liking eBay's Billpoint. Big companies also have restrictions that startups don't have to worry about. Adds Graham, "Microsoft has to think about web-based applications that don't threaten Windows. A company like Zenter doesn't care about hurting Windows. All they want to do is make the best application."

How a six-month-old startup got bought by Google [The Startup Game]